Application of Prohibitin Immunohistochemistry to Rat Livers Treated with Methapyrilene Hydrochloride

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Transport of dextran sulfates to rat livers.

Liver subcellular distributions of three different dextran sulfates (DSs) with average molecular weight (AMW) of 3000, 20,000, and 200,000, and sulfur content of 18%, anticoagulants and antilipemic agents, were examined in rats after intravenous administration of 50 mg/kg. About 20% of the injected radioactivity was taken up by liver 15 min-3 hr after 35S-DS administration, but the uptake of 35...

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Altered Cobalamin Distribution in Rat Hepatomas and in the Livers of Rats Treated with Diethylnitrosamine1

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Altered cobalamin distribution in rat hepatomas and in the livers of rats treated with diethylnitrosamine.

The distribution of cobalamin cofactors was investigated in the livers and tumors of rats bearing transplanted Morris 7777 or 7800 hepatomas, in the livers of rats treated with the hepatocarcinogen diethylnitrosamine, and in normal rats. There was a significant increase in the proportion of methylcobalamin both in livers and tumors from rat bearing the hepatomas 7777 and 7800 compared to the pr...

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Application of immunohistochemistry to soft tissue neoplasms.

CONTEXT Soft tissue tumors are composed of numerous and complex diagnostic entities. Because of this complexity and the recognition of an intermediate malignancy category including some tumors with a deceptively bland histologic appearance, soft tissue tumors may represent a major diagnostic challenge to the general practicing pathologist. OBJECTIVE To correctly diagnose soft tissue tumors wi...

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ژورنال

عنوان ژورنال: Journal of Toxicologic Pathology

سال: 2008

ISSN: 0914-9198,1881-915X

DOI: 10.1293/tox.21.119